Efficacy endpoint met in Phase II AML study
Lighthouse | 2 April 2019
Trinity Delta view: BerGenBio has already reported promising bemcentinib monotherapy data from this Phase II trial (CR/CRi/CRp rate of 22% from all 27 patients treated and 43% from the 14 patients with low levels of the sAxl biomarker, see Outlook note from January 2019). This data suggests that bemcentinib can also increase the activity of LDAC, the current standard of care for elderly AML patients and that has an ORR of only c18%.
Our valuation of BerGenBio is NOK3,143m ($370m) or NOK57.45/share and data from the Phase II study in NSCLC with pembrolizumab due in the coming months could be important share price catalysts. The overall survival data from the first stage of the Phase II study in NSCLC with pembrolizumab and initial results from the trial’s second stage are due in Q219.
2 April 2019
BerGenBio is a clinical-stage, drug development company based in Bergen, Norway and Oxford, UK. It is developing innovative anti-cancer therapies that act on the promising Axl signalling pathway. The lead oncology compound, bemcentinib, is in a number of Phase II trials.
Mick Cooper PhD
+44 (0) 20 3637 5042
+44 (0) 20 3637 5043
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